Conference Day One

7:15 am Check-in & Coffee

8:15 am Chair’s Opening Remarks

Nick Valiante Co-Founder & Chief Scientific Officer, Innovac Therapeutics

Unpacking 2024’s Successes & Anticipating the Next Challenges to Advance the Future of mRNA-Based Therapeutics & Vaccines

8:30 am CXOs’ Panel Discussion: Unlocking the Next Frontiers of mRNA-Based Vaccines & Therapeutics to Ensure Better Drugs Reach Patients Faster

Andrew Allen President, Chief Executive Officer & Co-Founder, Gritstone bio, Inc.
Nathaniel Wang Chief Executive Officer & Co-Founder, Replicate Bioscience
Sophia Lugo CEO, Radar Therapeutics
Nick Valiante Co-Founder & Chief Scientific Officer, Innovac Therapeutics
Trevor J Hallam CSO, Sail Biomedicines
Thaminda Ramanayake Chief Business Officer, CureVac

Synopsis

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9:30 am Clinical Safety & Impact of RNA Cell Therapy in Patients with Myasthenia Gravis

Chris Jewell Chief Scientific Officer, Cartesian Therapeutics New Data!

Synopsis

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10:00 am mRNA Therapeutics: Riding the Next Wave in Biotech

Aalok Shah Director, Resilience Inc

Synopsis

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10:30 am Morning Networking Break

Track 1: Discovery Track 2: Translation Track 3: Clinical Development Track 4: CMC

Track 1: Discovery

Discovery

Chair: Denny Kraichely, Global Program Leader, Vaccine Development Management, Pfizer

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Unlocking the Power of Next Generation Base Editors & Replicating mRNA for Pushing the Frontiers of mRNA

11:30am Advancing Next Generation Gene Editing with Beam Therapeutics’ Proprietary Next Generation Base Editor

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Luis Barrera, Senior Vice President, Data Sciences Beam Therapeutics New Data!

12:00pm Multimodal Support of mRNA Therapeutic Development

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Wayne Doyle, Head of Platform, Eclipse Bio

12:30pm Enabling Single-Dose, Multivalent Vaccination Against Pathogens of High Consequence Using a Muscle-Localizing Nanocarrier-Formulated Replicating mRNA

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Jesse Erasmus, Director, Virology, HDT Bio

1:00pm Accessing a Vast Design Space with a Modular High Throughput Platform for RNA Therapeutics & Vaccines

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Stephanie Khan, Director, Business Development, Ginkgo Bioworks

Track 2: Translation

Translation

Chair: Sam Deutsch, Chief Scientific Officer, Nutcracker Therapeutics

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Widening the Scope of mRNA with circRNA Vaccines & Therapeutics to Treat Infectious & Oncological Diseases

11:30am Introducing Orbital’s circRNA Vaccine Platform as a Novel Alternative to a Linear Vaccine

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Giles Besin, Chief Scientific Officer, Orbital Therapeutics

12:00pm Reduction of LNP-Associated Inflammation with Use of Biodegradable Lipids

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Syed Reza, Scientific & Sales Consultant, NOF CORPORATION

12:30pm In vivo panCARTM Therapy Using Circular RNA for the Treatment of B Cell Malignancies in Oncology & Autoimmune Disease

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Isin Dalkilic-Liddle, Senior Director & Head of Drug Discovery, Orna Therapeutics New Company!

Track 3: Clinical Development

Clinical Development

Chair: Igor Matushansky, Chief Medical Officer, Sail Biomedicines

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Advancing Neoantigen-Based mRNA Medicines in the Clinic to Effectively Treat Oncological Indications

11:30am Revealing Key Clinical Findings from Moderna’s Individualized Neoantigen Therapy Against Melanoma

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Kyle Holen, Head of Development, Oncology & Therapeutics, Moderna New Data!

12:00pm Mitigating Risk Through Development & Engineering Runs When Transitioning from Preclinical to Clinical Manufacturing

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Evan Myers, Associate Director, Process Development, TriLink BioTechnologies

12:30pm Neoantigen Immunotherapy for Solid Tumors: Molecular Responses & Clinical Benefit in Late-Stage Patients

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Andy Ferguson, Vice President, Clinical Science, Gritstone Bio New Data!

Track 4: CMC

Chemistry, Manufacturing & Controls

Chair: Francis Poulin, Vice President, Analytical Sciences, Sail Biomedicines

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Developing a Strategic Platform Approach to Ensure Robust Manufacturing Processes for mRNA-Based Drugs

11:30am Establishing an mRNA Vaccine Platform to Effectively Support a Broad Vaccine & Therapeutic Drug Portfolio

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Joshua Di Napoli, Global Project Head, mRNA platform Development, Sanofi

12:00pm Trehalose & Sucrose: Essential Components of Platform Biopharma Formulations & COVID-19 Applications

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Sudhakar Voruganti, Business Development Director, Pfanstiehl

12:30pm Leveraging Historic Know-How to Establish a Strategic Internal End-to-End Nucleic Acid Production Platform

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Emily Wen, Senior Principal Scientist, Merck & Co New Data!

1:00pm Session Reserved For: Etherna

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1:10 pm Lunch Networking Break

Track 1: Discovery Track 2: Translation Track 3: Clinical Development Track 4: CMC

Track 1: Discovery

Discovery

Advancing RNA Drug Development & Design with Next-Generation Discovery Platforms

2:15pm Introduction to Orna’s Proprietary IRES Discovery & Drug Design Platform for Durable & Sustainable circRNA Expression

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Allen Horthota, Head of Platform, Orna Therapeutics New Data!

2:45pm Novel Efficient Cap Analogs Development and Application for mRNA Therapeutics

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Junlan Ren, COO, Henovcom

3:15pm Development of an mRNA Platform to Fight Infectious Disease

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George Thom, Director, Discovery Sciences - (IVEB) mRNA, AstraZeneca

Track 2: Translation

Translation

Supercharging the Translation of Novel mRNA Therapeutics to Combat Cancer & Advance Regenerative Medicine

2:15pm Advancing Novel mRNA Therapeutics Through Discovery & Development Phases

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Sam Deutsch, Chief Scientific Officer, Nutcracker Therapeutics New Data!

2:45pm mRNA-Based Transcription Factor Delivery to In Vivo
Disease Models

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Hanae Toyonoga, Manager, Discovery Accelerator,
Astellas Pharma

3:15pm Advancing Onco-Selective mRNA Therapeutics with Kernal’s KR-335 Program to Kill Tumor Cells

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Manfred Kraus, Vice-President, Head of R&D Therapeutics, Kernal Biologics

Track 3: Clinical Development

Clinical Development

Supercharging the saRNA Vaccine Platforms Against Infectious Diseases to Improve Patient Outcomes

2:15pm Next Generation Self-Replicating RNA (srRNA) Drives Substantial Improvement in Infectious Disease Vaccines

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Nathaniel Wang, Chief Executive Officer, Replicate Bioscience New Data!

2:45pm Strategies for Navigating the Complexity & Diversity of RNA-Lipid Nanoparticles

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Ian Johnston, Field Application Scientist, Cytiva

3:15pm Comparing a Second-Generation saRNA Flu Vaccine with a Traditional mRNA
Flu Vaccine

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Cheng Chang, Associate Director, RNA Platform, CSL

Track 4: CMC

Chemistry, Manufacturing & Controls

Mission Possible: Showcasing Breakthrough mRNA Vaccine Initiatives to Establish Rapid Responses to Viral Pathogens

2:15pm RNA Vaccine Innovations for CEPI’s 100 Days Mission

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Dimki Patel, CMC Program Leader, CEPI

2:45pm Maximizing Success in mRNA Manufacturing: Key Considerations for Analytical Characterization

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Eunseo Ency Lee, Lead Scientist, mRNA Manufacturing Group, Samsung Biologics

3:15pm BAXERNA: On a Mission to Develop Novel Bacterial mRNA Vaccines

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Lyudmila Kovalchuke, Project Manager, VIB-UGent New Company!

3:45 pm Afternoon Networking Break & Poster Session

Track 1: Discovery Track 2: Translation Track 3: Clinical Development Track 4: CMC

Track 1: Discovery

Discovery

Advancing Next Generation mRNA Drug Development with Optimized mRNA-LNP Platforms to Enable Targeted Delivery

4:30pm Introducing ZipCode Bio’s Proprietary mRNA
Medicine Platform

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Jason Zhang, Co-Founder and CEO, Zipcode Bio

5:00pm Shedding Light on dsRNA: Specific & Sensitive Detection Using Bioluminescence

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Jamison Grailer, Senior Research Scientist, Promega

Track 2: Translation

Translation

Broadening the Horizons of mRNA Through Next Generation Replicating Vaccines & Therapeutics

4:30pm Improvements to the Self-Amplifying RNA Platform for Safer & More Effective Vaccines & Therapeutics

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Peter Berglund, Chief Scientific Officer, HDT Bio New Data!

5:00pm Presenting Johnson & Johnson’s Discovery & Pre-Clinical Work with saRNA for Vaccine & Therapeutic Applications

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Rachel Groppo, Director, Lead Self-Amplifying RNA Team, Johnson & Johnson Innovative Medicine

Track 3: Clinical Development

Clinical Development

Revealing the Latest Next Generation Infectious Disease
Vaccines to Open Up New Frontiers for mRNA

4:30pm Beyond Respiratory mRNA Vaccines: Moderna’s Norovirus
mRNA Vaccine Candidates

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Till Schoofs, Director, Clinical Development,
Infectious Diseases, Moderna

5:00pm Diving into the Analytical Characterization of in vitro Transcribed mRNAs

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Julien Camperi, Ph.D., Technical Development Principal Scientist - Gene & Cell Therapy, Genentech, A Member of the Roche Group

Track 4: CMC

Returning July 21-23, 2025 | Boston, MA
The Flagship Meeting of the
World RNA Series

Returning July 21-23, 2025 | Boston, MA
The Flagship Meeting of the World RNA Series

Tuesday July 30, 2024

7:15 am Check-in & Coffee

8:15 am Chair’s Opening Remarks

Unpacking 2024’s Successes & Anticipating the Next Challenges to Advance the Future of mRNA-Based Therapeutics & Vaccines

8:30 am CXOs’ Panel Discussion: Unlocking the Next Frontiers of mRNA-Based Vaccines & Therapeutics to Ensure Better Drugs Reach Patients Faster

Synopsis

9:30 am Clinical Safety & Impact of RNA Cell Therapy in Patients with Myasthenia Gravis

Synopsis

10:00 am mRNA Therapeutics: Riding the Next Wave in Biotech

Synopsis

10:30 am Morning Networking Break

1:10 pm Lunch Networking Break

3:45 pm Afternoon Networking Break & Poster Session

5:30 pm Drinks Reception Hosted by Thermo Fisher Scientific

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Returning July 21-23, 2025 | Boston, MAThe Flagship Meeting of the World RNA Series

Returning July 21-23, 2025 | Boston, MAThe Flagship Meeting of the World RNA Series