Bei Cheng
Associate Principal Scientist AstraZeneca
Seminars
Tuesday 21st July 2026
Stable In Vivo Expression of Monoclonal Antibody from Lyophilized mRNA–LNPs Stored at Room Temperature
2:30 pm
- Lyophilized mRNA–LNPs engineered for room‑temperature storage, maintaining physicochemical integrity, good in vitro transfection, and stable in vivo monoclonal antibody expression
- LNP internal structure determined for lyophilized formulations with different cryoprotectants and buffers using SAXS and cryo‑EM, linking structure to performance
