Breakthrough Innovations Workshop
Save millions of lives, trillions of dollars, and enable real global equity
Time: 3:45 pm
day: Pre-Conference Day
Details:
The R3: RNA Readiness and Response program, took a page from the semiconductor industry transformation in the 1980s, which developed multi-product foundries with standardized processes and design tools that exploded global innovation.
This session will cover R3 advances in:
- Manufacturing processes, with the potential for 10mg to 1kg of RNA-based product, or up to 100 products, per day, in a 35 m2 footprint
- Vaccines and therapeutic products that target >30X dose-reduction and >100X cost-reduction compared to state-of-the-art
- In-silico design tools that enable >5X dose-reduction and manufacturability verification with >90% accuracy, for a democratized access to the RNA Ecosystem
Key Takeaways
- Standardized, multiproduct, continuous RNA manufacturing processes enable GMP production of 100 milligram-scale RNA therapeutics, as well as 1 billion RNA vaccine doses, in one day, in less than 35 m2.
- Digital design and verification tools democratize access to RNA manufacturing providing >5X increase in biological performance and >90% accuracy in manufacturability prediction.
- The same fab-less / pure-play foundry model that developed the semiconductor industry, can now enable a vibrant, self-sustaining RNA Ecosystem providing equitable access to RNA-based products and economically sustainable pandemic preparedness.
