Hongjing Xia

Principal Scientist Novartis

Seminars

Monday 20th July 2026
BRAND NEW DATA icon
1:30 pm

Impact of mRNA Design on In Vivo Murine mRNA-LNP CD19 CAR in a Syngeneic Mouse Model

  • Syngeneic mouse models provide key advantages for preclinical evaluation of CAR‑T cell efficacy and biology
  • Functional murine CAR scFv identification and preliminary data on mCD8‑targeted LNP delivery
  • Optimization of murine CD19 CAR mRNA is required to further enhance performance
Hongjing Xia
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