APEXm™ (Amplified & Prolonged EXpression mRNA) is a Modular Linear mRNA Platform for Potent & Durable Therapeutic Protein Expression
- APEXm™ (Amplified and Prolonged EXpression mRNA) is a modular mRNA technology that confers potent and durable therapeutic protein expression from linear mRNA
- APEXm™ can be used to engineer mRNA for in vivo CAR-T applications, resulting in deep B-cell depletion from peripheral blood and lymphoid tissues in humanized mice and non-human primates
- APEXm™ enhances protein expression from any therapeutic mRNA across diverse cellular contexts and payloads, while maintaining simple manufacturing and compatibility with modified nucleotides