Overcoming the Innate Immune Response of Self-Amplifying RNAs to Unlock Improved Vaccines & Therapeutics

• The innate response to self-amplifying RNAs can by overcome by incorporating the right modified nucleotides
• Engineered saRNA vectors substantially increase protein expression, improving replication, stability, and translation
• Advanced vector designs unlock differentiated performance, enabling potent multivalent vaccines and tissue-specific therapeutic expression

Speakers:

Joshua McGee

CSO

Keylicon Biosciences