Engineered Bio-Reducible Lipid Nanoparticles Enable Highly Efficient mRNA Delivery to Bone Marrow Stem Cells
- New data on the follow up platform to the potent LNPs that outperform by at least 5-fold clinical benchmark LNP compounds in non-human primates for vaccine and liver repeat dose protein expression applications
- New LNPs that have been optimized for either efficient delivery of RNA payloads to hematopoietic stem and progenitor cells in the bone marrow
- Achieving mRNA payload expression in over 90% of all bone marrow HSCs