Development of Trans-Amplifying RNAs to Enable Robust Expression Across Multiple Species

• Trans-amplifying RNA (taRNA) combines the advantages of modified mRNA and self-amplifying RNAs
• taRNA leads to increased peak expression as compared to modified mRNA at a fraction of the total RNA dose
• Multiple datasets demonstrating the potency, tolerability, and species translatability of taRNA

Speakers:

Adam Dingens

Senior Director

Amplitude Therapeutics